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KMID : 0363819740080010025
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Korean Journal of Nuclear Medicine
1974 Volume.8 No. 1 p.25 ~ p.28
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Effect of Postural Change on Plasma Insulin Concentration in Normal Volunteer
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성호경/Sung, Hokyung
고주환/주종구/김진용/이장규/Koh, Joohwan/Joo, Jongkoo/Kim, Jinyong/Lee, Jangkyu
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Abstract
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The concentrations of some blood constituents are known to be influenced by the postural change.
The blood glucose and insulin concentrations were measured, first, in the supine, and then (30 minutes later) in the erect positions under the fasting state. The effects of a duretic, furcsemide, were also studied under the same condition for 5 consecutive days.
The materials were 5 healthy volunteers aging 20-29 years old with out any diabetic past, or family histories. The blood gb_ccse was measured by the Nelson´s method, and plasma insulin by the radioimmunoassay method.
Following are the results;
1. The plasma insulin concentration in the erect pcsition is slightly higher than in the supine position, however, the increase is statistically insignificant because of the notable individual variations in the values of the supine position.
2. Four out of 5 cases show the increase of about 80% of plasma insulin in the erect position,
which is statistically significant if analyzed on the basis of frequency distribution.
3. The blood glucose concentration showed no postural changes.
4. The increase of the plasma insulin concentration in the erect position seems to be the result
cf limited extra vasation of insulin in the lower extremities.
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